Cytomegalovirus infection

Definition:

Cytomegalovirus (CMV) is a double-stranded DNA virus of the Herpesviridae family acquired by late childhood in the majority of individuals. Primary infection is nonspecific but after that the virus becomes latent in multiple organs and can later be reactivated. CMV is an important and common cause of mortality and morbidity in immunocompromised patients such as those with HIV/AIDS or transplant recipients on immunosuppressive therapy.

References:

[1]. Cary Chisholm, et al. Cutaneous infections caused by Herpesviridae: a review. Arch Pathol Lab Med. 2011 Oct;135(10):1357-62. [Content Brief]

[2]. Jay A Fishman, et al. Infections in immunocompromised hosts and organ transplant recipients: essentials. Liver Transpl. 2011 Nov;17 Suppl 3:S34-7. [Content Brief]

[3]. Manisha Jain, et al. Cytomegalovirus infection in non-immunosuppressed critically ill patients. J Infect Dev Ctries. 2011 Aug 12;5(8):571-9. [Content Brief]

[4]. S A Ross, et al. Overview of the diagnosis of cytomegalovirus infection. Infect Disord Drug Targets. 2011 Oct;11(5):466-74. [Content Brief]

[5]. Sarah E Jackson, et al. Human cytomegalovirus immunity and immune evasion. Virus Res. 2011 May;157(2):151-60. [Content Brief]

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