Cytoplasmic phosphatidylinositol transfer protein 1
Definition:
[Isoform 1]: Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidic acid (PA) between membranes. Binds PA derived from the phospholipase D signaling pathway and among the cellular PA species, preferably binds to the C16:0/16:1 and C16:1/18:1 PA species.; [Isoform 2]: Catalyzes the transfer of phosphatidylinositol between membranes.
References:
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[1]. Y Fullwood, et al. Cloning and characterization of a novel human phosphatidylinositol transfer protein, rdgBbeta. J Biol Chem. 1999 Oct 29;274(44):31553-8. [Content Brief]
[2]. Kathryn Garner, et al. Phosphatidylinositol transfer protein, cytoplasmic 1 (PITPNC1) binds and transfers phosphatidic acid. J Biol Chem. 2012 Sep 14;287(38):32263-76. [Content Brief]
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