Cytosolic acyl coenzyme A thioester hydrolase

Definition:

Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Preferentially hydrolyzes palmitoyl-CoA, but has a broad specificity acting on other fatty acyl-CoAs with chain-lengths of C8-C18. May play an important physiological function in brain.

References:

[1]. J Yamada, et al. Purification, molecular cloning, and genomic organization of human brain long-chain acyl-CoA hydrolase. J Biochem. 1999 Dec;126(6):1013-9. [Content Brief]

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