DET1- and DDB1-associated protein 1
Definition:
References:
-
[1]. Taisuke Uehara, et al. Selective degradation of splicing factor CAPERα by anticancer sulfonamides. Nat Chem Biol. 2017 Jun;13(6):675-680. [Content Brief]
[2]. Tyler B Faust, et al. Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nat Chem Biol. 2020 Jan;16(1):7-14. [Content Brief]
[3]. Dirksen E Bussiere, et al. Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex. Nat Chem Biol. 2020 Jan;16(1):15-23. [Content Brief]
[4]. Ting Han, et al. Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15. Science. 2017 Apr 28;356(6336):eaal3755. [Content Brief]
[5]. Elah Pick, et al. Mammalian DET1 regulates Cul4A activity and forms stable complexes with E2 ubiquitin-conjugating enzymes. Mol Cell Biol. 2007 Jul;27(13):4708-19. [Content Brief]
Molarity Calculator
Dilution Calculator
