DNA transposase THAP9

Definition:

Active transposase that specifically recognizes the bipartite 5'-TXXGGGX(A/T)-3' consensus motif and mediates transposition.

References:

[1]. Sharmistha Majumdar, et al. The human THAP9 gene encodes an active P-element DNA transposase. Science. 2013 Jan 25;339(6118):446-8. [Content Brief]

[2]. Alex Sabogal, et al. THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves. Nat Struct Mol Biol. 2010 Jan;17(1):117-23. [Content Brief]

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