Dual specificity protein phosphatase 16

Definition:

Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2.

References:

[1]. K Masuda, et al. MKP-7, a novel mitogen-activated protein kinase phosphatase, functions as a shuttle protein. J Biol Chem. 2001 Oct 19;276(42):39002-11. [Content Brief]

[2]. Emma A Willoughby, et al. Dynamic interaction between the dual specificity phosphatase MKP7 and the JNK3 scaffold protein beta-arrestin 2. J Biol Chem. 2005 Jul 8;280(27):25651-8. [Content Brief]

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