Engulfment and cell motility protein 2
Definition:
References:
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[1]. Nao Hiramoto-Yamaki, et al. Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism. J Cell Biol. 2010 Aug 9;190(3):461-77. [Content Brief]
[2]. T L Gumienny, et al. CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration. Cell. 2001 Oct 5;107(1):27-41. [Content Brief]
[3]. Z Zhou, et al. The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway. Dev Cell. 2001 Oct;1(4):477-89. [Content Brief]
[4]. Arda Cetinkaya, et al. Loss-of-Function Mutations in ELMO2 Cause Intraosseous Vascular Malformation by Impeding RAC1 Signaling. Am J Hum Genet. 2016 Aug 4;99(2):299-317. [Content Brief]