country

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

ER lumen protein-retaining receptor 2

Definition:

Membrane receptor that binds the K-D-E-L sequence motif in the C-terminal part of endoplasmic reticulum resident proteins and maintains their localization in that compartment by participating to their vesicle-mediated recycling back from the Golgi. Binding is pH dependent, and is optimal at pH 5-5.4 (By similarity).

References:

[1]. M J Lewis, et al. Sequence of a second human KDEL receptor. J Mol Biol. 1992 Aug 20;226(4):913-6. [Content Brief]

[2]. Irina Raykhel, et al. A molecular specificity code for the three mammalian KDEL receptors. J Cell Biol. 2007 Dec 17;179(6):1193-204. [Content Brief]

[3]. Fleur S van Dijk, et al. Interaction between KDELR2 and HSP47 as a Key Determinant in Osteogenesis Imperfecta Caused by Bi-allelic Variants in KDELR2. Am J Hum Genet. 2020 Nov 5;107(5):989-999. [Content Brief]

Biomedical Dictionary

The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #