Eukaryotic translation initiation factor 4E type 2
Definition:
References:
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[1]. E Rom, et al. Cloning and characterization of 4EHP, a novel mammalian eIF4E-related cap-binding protein. J Biol Chem. 1998 May 22;273(21):13104-9. [Content Brief]
[2]. Clément Chapat, et al. Cap-binding protein 4EHP effects translation silencing by microRNAs. Proc Natl Acad Sci U S A. 2017 May 23;114(21):5425-5430. [Content Brief]
[3]. Masahiro Morita, et al. A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development. Mol Cell Biol. 2012 Sep;32(17):3585-93. [Content Brief]
[4]. Pamela Rosettani, et al. Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms. J Mol Biol. 2007 May 4;368(3):691-705. [Content Brief]
[5]. Louise von Stechow, et al. The E3 ubiquitin ligase ARIH1 protects against genotoxic stress by initiating a 4EHP-mediated mRNA translation arrest. Mol Cell Biol. 2015 Apr;35(7):1254-68. [Content Brief]
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