Huntington's diseases (HD)

Definition:

Huntington's disease (HD) is a heritable and fatal Neurodegenerative diseases (NDDs) characterized by a triad of motor, cognitive and neuropsychiatric symptoms. A common and particularly detrimental neuropsychiatric alteration in HD gene carriers is irritability, which frequently manifests as abrupt and unpredictable outbursts of anger.

References:

[1]. Karagas NE, et al. Irritability in Huntington's Disease. J Huntingtons Dis. 2020;9(2):107-113. [Content Brief]

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