JmjC domain-containing protein 8
Definition:
Functions as a positive regulator of TNF-induced NF-kappa-B signaling. Regulates angiogenesis and cellular metabolism through interaction with PKM.
References:
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[1]. Kok Siong Yeo, et al. JMJD8 is a positive regulator of TNF-induced NF-κB signaling. Sci Rep. 2016 Sep 27;6:34125. [Content Brief]
[2]. Jes-Niels Boeckel, et al. JMJD8 Regulates Angiogenic Sprouting and Cellular Metabolism by Interacting With Pyruvate Kinase M2 in Endothelial Cells. Arterioscler Thromb Vasc Biol. 2016 Jul;36(7):1425-33. [Content Brief]
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