Kinesin-like protein KIF18B
Definition:
In complex with KIF2C, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Its major role may be to transport KIF2C and/or MAPRE1 along microtubules.
References:
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[1]. Young Mi Lee, et al. Cell cycle-regulated expression and subcellular localization of a kinesin-8 member human KIF18B. Gene. 2010 Oct 15;466(1-2):16-25. [Content Brief]
[2]. Marvin E Tanenbaum, et al. A complex of Kif18b and MCAK promotes microtubule depolymerization and is negatively regulated by Aurora kinases. Curr Biol. 2011 Aug 23;21(16):1356-65. [Content Brief]
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