Kinesin-like protein KIF2B

Definition:

Plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement. Has microtubule depolymerization activity. Plays a role in chromosome congression.

References:

[1]. Amity L Manning, et al. The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells. Mol Biol Cell. 2007 Aug;18(8):2970-9. [Content Brief]

[2]. Roshan L Shrestha, et al. Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK. Curr Biol. 2013 Aug 19;23(16):1514-26. [Content Brief]

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