Leucine-rich repeat-containing protein 52
Definition:
Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium. KCNU1 channel auxiliary protein. May modulate KCNU1 gating properties.
References:
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[1]. Jiusheng Yan, et al. BK potassium channel modulation by leucine-rich repeat-containing proteins. Proc Natl Acad Sci U S A. 2012 May 15;109(20):7917-22. [Content Brief]
[2]. Manuel D Leonetti, et al. Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel. Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19274-9. [Content Brief]
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