Mitochondrial proton/calcium exchanger protein
Definition:
References:
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[1]. Dawei Jiang, et al. Genome-wide RNAi screen identifies Letm1 as a mitochondrial Ca2+/H+ antiporter. Science. 2009 Oct 2;326(5949):144-7. [Content Brief]
[2]. Shoko Tamai, et al. Characterization of the mitochondrial protein LETM1, which maintains the mitochondrial tubular shapes and interacts with the AAA-ATPase BCS1L. J Cell Sci. 2008 Aug 1;121(Pt 15):2588-600. [Content Brief]
[3]. Umberto De Marchi, et al. NCLX protein, but not LETM1, mediates mitochondrial Ca2+ extrusion, thereby limiting Ca2+-induced NAD(P)H production and modulating matrix redox state. J Biol Chem. 2014 Jul 18;289(29):20377-85. [Content Brief]