Mouse double minute 2 homolog (MDM2)

Definition:

Mouse double minute 2 homolog (MDM2) is an E3 ubiquitin ligase, has been identified as an oncoprotein that mediates the ubiquitination and degradation of tumor suppressor p53.

References:

[1]. Wang A, et al. Mouse Double Minute 2 Homolog-Mediated Ubiquitination Facilitates Forkhead Box P3 Stability and Positively Modulates Human Regulatory T Cell Function. Front Immunol. 2020 Jun 19;11:1087. [Content Brief]

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