1. Biology Dictionary
  2. Myc-associated zinc finger protein

Myc-associated zinc finger protein

Definition:

Transcriptional regulator, potentially with dual roles in transcription initiation and termination.; [Isoform 1]: Binds DNA and functions as a transcriptional activator. Binds to two G/A-rich sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors.; [Isoform 2]: Binds DNA and functions as a transcriptional activator. Inhibits MAZ isoform 1-mediated transcription.; [Isoform 3]: Binds DNA and functions as a transcriptional activator.

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