Neutral amino acid transporter A

Definition:

Sodium-dependent neutral amino-acid transporter that mediates transport of alanine, serine, cysteine, proline, hydroxyproline and threonine.

References:

[1]. J Pinilla-Tenas, et al. Transport of proline and hydroxyproline by the neutral amino-acid exchanger ASCT1. J Membr Biol. 2003 Sep 1;195(1):27-32. [Content Brief]

[2]. Nadirah Damseh, et al. Mutations in SLC1A4, encoding the brain serine transporter, are associated with developmental delay, microcephaly and hypomyelination. J Med Genet. 2015 Aug;52(8):541-7. [Content Brief]

[3]. J L Arriza, et al. Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family. J Biol Chem. 1993 Jul 25;268(21):15329-32. [Content Brief]

[4]. S Shafqat, et al. Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters. J Biol Chem. 1993 Jul 25;268(21):15351-5. [Content Brief]

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