P2Y purinoceptor 12
Definition:
References:
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[1]. Jin Zhang, et al. Agonist-bound structure of the human P2Y12 receptor. Nature. 2014 May 1;509(7498):119-22. [Content Brief]
[2]. Kaihua Zhang, et al. Structure of the human P2Y12 receptor in complex with an antithrombotic drug. Nature. 2014 May 1;509(7498):115-8. [Content Brief]
[3]. F L Zhang, et al. ADP is the cognate ligand for the orphan G protein-coupled receptor SP1999. J Biol Chem. 2001 Mar 16;276(11):8608-15. [Content Brief]
[4]. G Hollopeter, et al. Identification of the platelet ADP receptor targeted by antithrombotic drugs. Nature. 2001 Jan 11;409(6817):202-7. [Content Brief]
[5]. J Takasaki, et al. Molecular cloning of the platelet P2T(AC) ADP receptor: pharmacological comparison with another ADP receptor, the P2Y(1) receptor. Mol Pharmacol. 2001 Sep;60(3):432-9. [Content Brief]
[6]. Marco Cattaneo, et al. Molecular bases of defective signal transduction in the platelet P2Y12 receptor of a patient with congenital bleeding. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1978-83. [Content Brief]