Phenylethanolamine N-methyltransferase
Definition:
References:
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[1]. Yuan Ji, et al. Human phenylethanolamine N-methyltransferase pharmacogenomics: gene re-sequencing and functional genomics. J Neurochem. 2005 Dec;95(6):1766-76. [Content Brief]
[2]. J M Caine, et al. Recombinant human phenylethanolamine N-methyltransferase: overproduction in Escherichia coli, purification, and characterization. Protein Expr Purif. 1996 Sep;8(2):160-6. [Content Brief]
[3]. Christine L Gee, et al. Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis. Biochemistry. 2005 Dec 27;44(51):16875-85. [Content Brief]
[4]. Dong-Il Kang, et al. Discovery of novel human phenylethanolamine N-methyltransferase (hPNMT) inhibitors using 3D pharmacophore-based in silico, biophysical screening and enzymatic activity assays. Mol Cells. 2010 Jun;29(6):595-602. [Content Brief]