Proton-coupled zinc antiporter SLC30A2
Definition:
References:
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[1]. Stephen R Hennigar, et al. TNFα Post-Translationally Targets ZnT2 to Accumulate Zinc in Lysosomes. J Cell Physiol. 2015 Oct;230(10):2345-50. [Content Brief]
[2]. Young Ah Seo, et al. A histidine-rich motif mediates mitochondrial localization of ZnT2 to modulate mitochondrial function. Am J Physiol Cell Physiol. 2011 Jun;300(6):C1479-89. [Content Brief]
[3]. Veronica Lopez, et al. Zinc transporter-2 (ZnT2) variants are localized to distinct subcellular compartments and functionally transport zinc. Biochem J. 2009 Jul 29;422(1):43-52. [Content Brief]
[4]. Yarden Golan, et al. ZnT2 is an electroneutral proton-coupled vesicular antiporter displaying an apparent stoichiometry of two protons per zinc ion. PLoS Comput Biol. 2019 Mar 20;15(3):e1006882. [Content Brief]
[5]. Inbal Lasry, et al. A dominant negative heterozygous G87R mutation in the zinc transporter, ZnT-2 (SLC30A2), results in transient neonatal zinc deficiency. J Biol Chem. 2012 Aug 24;287(35):29348-61. [Content Brief]
[6]. Winyoo Chowanadisai, et al. Identification of a mutation in SLC30A2 (ZnT-2) in women with low milk zinc concentration that results in transient neonatal zinc deficiency. J Biol Chem. 2006 Dec 22;281(51):39699-707. [Content Brief]
[7]. Yarden Golan, et al. Heterodimerization, altered subcellular localization, and function of multiple zinc transporters in viable cells using bimolecular fluorescence complementation. J Biol Chem. 2015 Apr 3;290(14):9050-63. [Content Brief]
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