Radical S-adenosyl methionine domain-containing protein 2
Definition:
References:
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[1]. Abdul A Waheed, et al. Influenza virus not cRAFTy enough to dodge viperin. Cell Host Microbe. 2007 Aug 16;2(2):71-2. [Content Brief]
[2]. Chunyu Wei, et al. Viperin Inhibits Enterovirus A71 Replication by Interacting with Viral 2C Protein. Viruses. 2018 Dec 26;11(1):13. [Content Brief]
[3]. Anthony S Gizzi, et al. A naturally occurring antiviral ribonucleotide encoded by the human genome. Nature. 2018 Jun;558(7711):610-614. [Content Brief]
[4]. Yukang Yuan, et al. Targeting UBE4A Revives Viperin Protein in Epithelium to Enhance Host Antiviral Defense. Mol Cell. 2020 Feb 20;77(4):734-747.e7. [Content Brief]
[5]. Bénédicte Vanwalscappel, et al. A Viperin Mutant Bearing the K358R Substitution Lost its Anti-ZIKA Virus Activity. Int J Mol Sci. 2019 Mar 29;20(7):1574. [Content Brief]
[6]. Yugen Zhang, et al. Identification and characterization of interferon-induced proteins that inhibit alphavirus replication. J Virol. 2007 Oct;81(20):11246-55. [Content Brief]
[7]. Mark A Rivieccio, et al. TLR3 ligation activates an antiviral response in human fetal astrocytes: a role for viperin/cig5. J Immunol. 2006 Oct 1;177(7):4735-41. [Content Brief]
[8]. Meili Li, et al. The Interaction Mechanism Between Herpes Simplex Virus 1 Glycoprotein D and Host Antiviral Protein Viperin. Front Immunol. 2019 Dec 11;10:2810. [Content Brief]
[9]. Karla J Helbig, et al. Analysis of ISG expression in chronic hepatitis C identifies viperin as a potential antiviral effector. Hepatology. 2005 Sep;42(3):702-10. [Content Brief]
[10]. K C Chin, et al. Viperin (cig5), an IFN-inducible antiviral protein directly induced by human cytomegalovirus. Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):15125-30. [Content Brief]
[11]. Arti B Dumbrepatil, et al. Viperin interacts with the kinase IRAK1 and the E3 ubiquitin ligase TRAF6, coupling innate immune signaling to antiviral ribonucleotide synthesis. J Biol Chem. 2019 Apr 26;294(17):6888-6898. [Content Brief]
[12]. Ella R Hinson, et al. The N-terminal amphipathic alpha-helix of viperin mediates localization to the cytosolic face of the endoplasmic reticulum and inhibits protein secretion. J Biol Chem. 2009 Feb 13;284(7):4705-12. [Content Brief]