Ras-related GTP-binding protein A
Definition:
References:
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[1]. Lu Deng, et al. The ubiquitination of rag A GTPase by RNF152 negatively regulates mTORC1 activation. Mol Cell. 2015 Jun 4;58(5):804-18. [Content Brief]
[2]. E Hirose, et al. RagA is a functional homologue of S. cerevisiae Gtr1p involved in the Ran/Gsp1-GTPase pathway. J Cell Sci. 1998 Jan;111 ( Pt 1):11-21. [Content Brief]
[3]. Zhi-Yang Tsun, et al. The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1. Mol Cell. 2013 Nov 21;52(4):495-505. [Content Brief]
[4]. Simon A Fromm, et al. Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9. Nat Struct Mol Biol. 2020 Nov;27(11):1017-1023. [Content Brief]
[5]. Yasemin Sancak, et al. Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell. 2010 Apr 16;141(2):290-303. [Content Brief]
[6]. Y Li, et al. Interaction of an adenovirus 14.7-kilodalton protein inhibitor of tumor necrosis factor alpha cytolysis with a new member of the GTPase superfamily of signal transducers. J Virol. 1997 Feb;71(2):1576-82. [Content Brief]
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