Receptor operated channels (ROC)

Definition:

Receptor operated channels (ROC) is a cation channel that contributes to phospholipase C-dependent Ca²⁺ entry following stimulation of G-protein-coupled receptors or receptor tyrosine kinases.

References:

[1]. Plant TD, et al. Receptor-operated cation channels formed by TRPC4 and TRPC5. Naunyn Schmiedebergs Arch Pharmacol. 2005 Apr;371(4):266-76. [Content Brief]

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