Rho guanine nucleotide exchange factor 1
Definition:
References:
-
[1]. T Kozasa, et al. p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13. Science. 1998 Jun 26;280(5372):2109-11. [Content Brief]
[2]. Amine Bouafia, et al. Loss of ARHGEF1 causes a human primary antibody deficiency. J Clin Invest. 2019 Mar 1;129(3):1047-1060. [Content Brief]
[3]. M J Hart, et al. Identification of a novel guanine nucleotide exchange factor for the Rho GTPase. J Biol Chem. 1996 Oct 11;271(41):25452-8. [Content Brief]
[4]. M J Hart, et al. Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13. Science. 1998 Jun 26;280(5372):2112-4. [Content Brief]
[5]. Christophe Guilluy, et al. The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure. Nat Med. 2010 Feb;16(2):183-90. [Content Brief]