Ribosomal protein S6 kinase beta-2

Definition:

Phosphorylates specifically ribosomal protein S6. Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7.

References:

[1]. Joe Truong Nguyen, et al. Mammalian EAK-7 activates alternative mTOR signaling to regulate cell proliferation and migration. Sci Adv. 2018 May 9;4(5):eaao5838. [Content Brief]

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