RNA polymerase I-specific transcription initiation factor RRN3
Definition:
References:
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[1]. G Miller, et al. hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters. EMBO J. 2001 Mar 15;20(6):1373-82. [Content Brief]
[2]. B Moorefield, et al. RNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and human. Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4724-9. [Content Brief]
[3]. J Bodem, et al. TIF-IA, the factor mediating growth-dependent control of ribosomal RNA synthesis, is the mammalian homolog of yeast Rrn3p. EMBO Rep. 2000 Aug;1(2):171-5. [Content Brief]
[4]. Christine Mayer, et al. The nucleolus as a stress sensor: JNK2 inactivates the transcription factor TIF-IA and down-regulates rRNA synthesis. Genes Dev. 2005 Apr 15;19(8):933-41. [Content Brief]
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