Short hairpin RNAs (shRNAs)

Definition:

Short hairpin RNAs (shRNAs)is an artificial RNA molecule with a tight hairpin turn that can be used to silence target gene expression via RNA interference (RNAi).

References:

[1]. Paddison PJ, et al. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 2002 Apr 15;16(8):948-58. [Content Brief]

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