Sodium/potassium/calcium exchanger 2

Definition:

Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Required for learming and memory by regulating neuronal Ca(2+), which is essential for the development of synaptic plasticity (By similarity).

References:

[1]. Ali H Jalloul, et al. Cation dependencies and turnover rates of the human K⁺-dependent Na⁺-Ca²⁺ exchangers NCKX1, NCKX2, NCKX3 and NCKX4. Cell Calcium. 2016 Jan;59(1):1-11. [Content Brief]

[2]. C F Prinsen, et al. Molecular cloning and functional expression of the potassium-dependent sodium-calcium exchanger from human and chicken retinal cone photoreceptors. J Neurosci. 2000 Feb 15;20(4):1424-34. [Content Brief]

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