Sushi domain-containing protein 2

Definition:

May be a cytokine receptor for GPR15LG. May be a tumor suppressor; together with GPR15LG has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest. May play a role in breast tumorigenesis.

References:

[1]. Allison P Watson, et al. Multiple functions of sushi domain containing 2 (SUSD2) in breast tumorigenesis. Mol Cancer Res. 2013 Jan;11(1):74-85. [Content Brief]

[2]. Wen Pan, et al. CSBF/C10orf99, a novel potential cytokine, inhibits colon cancer cell growth through inducing G1 arrest. Sci Rep. 2014 Oct 29;4:6812. [Content Brief]

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