Triggering receptor expressed on myeloid cells 1
Definition:
References:
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[1]. Rob J W Arts, et al. TREM-1 interaction with the LPS/TLR4 receptor complex. Eur Cytokine Netw. 2011 Mar;22(1):11-4. [Content Brief]
[2]. Tereza Ormsby, et al. Btk is a positive regulator in the TREM-1/DAP12 signaling pathway. Blood. 2011 Jul 28;118(4):936-45. [Content Brief]
[3]. A Bouchon, et al. TREM-1 amplifies inflammation and is a crucial mediator of septic shock. Nature. 2001 Apr 26;410(6832):1103-7. [Content Brief]
[4]. Sergei Radaev, et al. Crystal structure of the human myeloid cell activating receptor TREM-1. Structure. 2003 Dec;11(12):1527-35. [Content Brief]
[5]. Christine B Read, et al. Cutting Edge: identification of neutrophil PGLYRP1 as a ligand for TREM-1. J Immunol. 2015 Feb 15;194(4):1417-21. [Content Brief]
[6]. Kevin Carrasco, et al. TREM-1 multimerization is essential for its activation on monocytes and neutrophils. Cell Mol Immunol. 2019 May;16(5):460-472. [Content Brief]
[7]. Sankar Baruah, et al. Identification of a Novel Splice Variant Isoform of TREM-1 in Human Neutrophil Granules. J Immunol. 2015 Dec 15;195(12):5725-31. [Content Brief]
[8]. Rabab El Mezayen, et al. Endogenous signals released from necrotic cells augment inflammatory responses to bacterial endotoxin. Immunol Lett. 2007 Jul 31;111(1):36-44. [Content Brief]
[9]. A Bouchon, et al. Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes. J Immunol. 2000 May 15;164(10):4991-5. [Content Brief]
[10]. Carl F Fortin, et al. Effects of TREM-1 activation in human neutrophils: activation of signaling pathways, recruitment into lipid rafts and association with TLR4. Int Immunol. 2007 Jan;19(1):41-50. [Content Brief]
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