Tyrosine-protein kinase JAK1

[1]. M Sakatsume, et al. The Jak kinases differentially associate with the alpha and beta (accessory factor) chains of the interferon gamma receptor to form a functional receptor unit capable of activating STAT transcription factors. J Biol Chem. 1995 Jul 21;270(29):17528-34. [Content Brief]

[2]. D Novick, et al. Soluble and membrane-anchored forms of the human IFN-alpha/beta receptor. J Leukoc Biol. 1995 May;57(5):712-8. [Content Brief]

[3]. Paul D Simoncic, et al. The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3. Curr Biol. 2002 Mar 19;12(6):446-53. [Content Brief]

[4]. Anna Usacheva, et al. Two distinct domains within the N-terminal region of Janus kinase 1 interact with cytokine receptors. J Immunol. 2002 Aug 1;169(3):1302-8. [Content Brief]

[5]. M Müller, et al. The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction. Nature. 1993 Nov 11;366(6451):129-35. [Content Brief]

[6]. Judith Staerk, et al. JAK1 and Tyk2 activation by the homologous polycythemia vera JAK2 V617F mutation: cross-talk with IGF1 receptor. J Biol Chem. 2005 Dec 23;280(51):41893-9. [Content Brief]

[7]. Kate L Del Bel, et al. JAK1 gain-of-function causes an autosomal dominant immune dysregulatory and hypereosinophilic syndrome. J Allergy Clin Immunol. 2017 Jun;139(6):2016-2020.e5. [Content Brief]

[8]. Conor N Gruber, et al. Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function. Immunity. 2020 Sep 15;53(3):672-684.e11. [Content Brief]

[9]. F W Quelle, et al. Phosphorylation and activation of the DNA binding activity of purified Stat1 by the Janus protein-tyrosine kinases and the epidermal growth factor receptor. J Biol Chem. 1995 Sep 1;270(35):20775-80. [Content Brief]