Ubiquitin-protein ligase E3A

[1]. I Louria-Hayon, et al. E6AP promotes the degradation of the PML tumor suppressor. Cell Death Differ. 2009 Aug;16(8):1156-66. [Content Brief]

[2]. Amit Mishra, et al. UBE3A/E6-AP regulates cell proliferation by promoting proteasomal degradation of p27. Neurobiol Dis. 2009 Oct;36(1):26-34. [Content Brief]

[3]. S Kumar, et al. Identification of HHR23A as a substrate for E6-associated protein-mediated ubiquitination. J Biol Chem. 1999 Jun 25;274(26):18785-92. [Content Brief]

[4]. Tetsu Shimoji, et al. Identification of annexin A1 as a novel substrate for E6AP-mediated ubiquitylation. J Cell Biochem. 2009 Apr 15;106(6):1123-35. [Content Brief]

[5]. Gustavo Martínez-Noël, et al. Identification and proteomic analysis of distinct UBE3A/E6AP protein complexes. Mol Cell Biol. 2012 Aug;32(15):3095-106. [Content Brief]

[6]. Virginia P Ronchi, et al. The active form of E6-associated protein (E6AP)/UBE3A ubiquitin ligase is an oligomer. J Biol Chem. 2014 Jan 10;289(2):1033-48. [Content Brief]

[7]. J M Huibregtse, et al. Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53. Mol Cell Biol. 1993 Feb;13(2):775-84. [Content Brief]

[8]. Nicole C Gossan, et al. The E3 ubiquitin ligase UBE3A is an integral component of the molecular circadian clock through regulating the BMAL1 transcription factor. Nucleic Acids Res. 2014 May;42(9):5765-75. [Content Brief]

[9]. Sarath C Dhananjayan, et al. WW domain binding protein-2, an E6-associated protein interacting protein, acts as a coactivator of estrogen and progesterone receptors. Mol Endocrinol. 2006 Oct;20(10):2343-54. [Content Brief]

[10]. Amit Mishra, et al. The ubiquitin ligase E6-AP is induced and recruited to aggresomes in response to proteasome inhibition and may be involved in the ubiquitination of Hsp70-bound misfolded proteins. J Biol Chem. 2009 Apr 17;284(16):10537-45. [Content Brief]