1. Biology Dictionary
  2. WD repeat and FYVE domain-containing protein 1

WD repeat and FYVE domain-containing protein 1

Definition:

Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines.

Biomedical Dictionary

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