Zinc finger protein 341

Definition:

Transcriptional activator of STAT3 involved in the regulation of immune homeostasis. Also able to activate STAT1 transcription.

References:

[1]. Stefanie Frey-Jakobs, et al. ZNF341 controls STAT3 expression and thereby immunocompetence. Sci Immunol. 2018 Jun 15;3(24):eaat4941. [Content Brief]

[2]. Vivien Béziat, et al. A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity. Sci Immunol. 2018 Jun 15;3(24):eaat4956. [Content Brief]

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