Zinc finger protein ZXDC

Definition:

Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.

References:

[1]. Wafa Al-Kandari, et al. ZXDC, a novel zinc finger protein that binds CIITA and activates MHC gene transcription. Mol Immunol. 2007 Jan;44(4):311-21. [Content Brief]

[2]. Srikarthika Jambunathan, et al. Sumoylation of the zinc finger protein ZXDC enhances the function of its transcriptional activation domain. Biol Chem. 2007 Sep;388(9):965-72. [Content Brief]

[3]. Wafa Al-Kandari, et al. The zinc finger proteins ZXDA and ZXDC form a complex that binds CIITA and regulates MHC II gene transcription. J Mol Biol. 2007 Jun 22;369(5):1175-87. [Content Brief]

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