Buphanidrine
Buphanidrine is an acetylcholinesterase (AChE) inhibitor with an IC50 of 52.8 μM. Buphanidrine can be extracted from Brunsvigia josephinae and has potential applications in Alzheimer's disease research.
For research use only. We do not sell to patients.
- CAS No.: 1162-10-3
- Formula: C18H21NO4
- Molecular Weight:315.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BJ | IC50 |
26.2 μM
Compound: 15
|
Cytotoxicity against human BJ cells after 72 hrs by Calcein AM assay
Cytotoxicity against human BJ cells after 72 hrs by Calcein AM assay
|
[PMID: 22921081] |
| CCRF-CEM | IC50 |
>50 μM
Compound: 15
|
Cytotoxicity against human CEM cells after 72 hrs by Calcein AM assay
Cytotoxicity against human CEM cells after 72 hrs by Calcein AM assay
|
[PMID: 22921081] |
| G-361 | IC50 |
>50 μM
Compound: 15
|
Cytotoxicity against human G361 cells after 72 hrs by Calcein AM assay
Cytotoxicity against human G361 cells after 72 hrs by Calcein AM assay
|
[PMID: 22921081] |
| HeLa | IC50 |
>50 μM
Compound: 15
|
Cytotoxicity against human HeLa cells after 72 hrs by Calcein AM assay
Cytotoxicity against human HeLa cells after 72 hrs by Calcein AM assay
|
[PMID: 22921081] |
| K562 | IC50 |
>50 μM
Compound: 15
|
Cytotoxicity against human K562 cells after 72 hrs by Calcein AM assay
Cytotoxicity against human K562 cells after 72 hrs by Calcein AM assay
|
[PMID: 22921081] |
| MCF7 | IC50 |
>50 μM
Compound: 15
|
Cytotoxicity against human MCF7 cells after 72 hrs by Calcein AM assay
Cytotoxicity against human MCF7 cells after 72 hrs by Calcein AM assay
|
[PMID: 22921081] |
Chemical Information
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CAS No. 1162-10-3
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Molecular Weight 315.36
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Formula C18H21NO4
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SMILES
COC1=C2C([C@]34[C@](C[C@H](C=C4)OC)([H])[N@](C2)CC3)=CC5=C1OCO5
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)