1005497-03-9
Chemical Structure
Acid Ceramidase-IN-2
- CAS No.: 1005497-03-9
- Formula:C30H47NO6
- Molecular Weight:517.70
IUPAC Name: N-((2S,3R)-1,3-dihydroxy-5-((2-oxo-2H-chromen-7-yl)oxy)pentan-2-yl)palmitamide
InChIKey: ASWQERQPSVCZCY-RRPNLBNLSA-N
SMILES: CCCCCCCCCCCCCCCC(N[C@@H](CO)[C@H](O)CCOC1=CC=C(C=CC(O2)=O)C2=C1)=O
Biological Activity: Acid Ceramidase-IN-2 (compound 1) is an acid ceramidase inhibitor with potentially antiproliferative and cytostatic activities. Moreover, human acid ceramidase is overexpressed in prostate cancer cells, indicating potential anti-tumor effect of Acid Ceramidase-IN-2. And Acid Ceramidase-IN-2 hydrolysis can be inhibited by 3 a-ketoamides GT85, GT98 and GT99 inhibits in vitro[1].
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Acid Ceramidase-IN-2 | 99.0% | Acid Ceramidase-IN-2 (compound 1) is an acid ceramidase inhibitor with potentially antiproliferative and cytostatic activities. Moreover, human acid ceramidase is overexpressed in prostate cancer cells, indicating potential anti-tumor effect of Acid Ceramidase-IN-2. And Acid Ceramidase-IN-2 hydrolysis can be inhibited by 3 a-ketoamides GT85, GT98 and GT99 inhibits in vitro. | ||||||||||||||||||||
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