1022150-57-7
1022150-57-7
Chemical Structure
SGX-523
- CAS No.: 1022150-57-7
- Formula:C18H13N7S
- Molecular Weight:359.41
IUPAC Name: 6-((6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)thio)quinoline
InChIKey: BCZUAADEACICHN-UHFFFAOYSA-N
SMILES: CN1N=CC(C2=NN3C(SC4=CC5=C(N=CC=C5)C=C4)=NN=C3C=C2)=C1
Biological Activity: SGX523 is a exquisitely selective and ATP-competitive MET inhibitor. SGX523 potently inhibits MET with an IC50 of 4 nM and is >1,000-fold selective versus other protein kinases. Antitumor activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SGX-523 | 99.51% | SGX523 is a exquisitely selective and ATP-competitive MET inhibitor. SGX523 potently inhibits MET with an IC50 of 4 nM and is >1,000-fold selective versus other protein kinases. Antitumor activity. | ||||||||||||||||||||
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References
Keywords
