102612-16-8
Chemical Structure
L-656224
- CAS No.: 102612-16-8
- Formula:C20H21ClO3
- Molecular Weight:344.83
IUPAC Name: 7-chloro-2-(4-methoxybenzyl)-3-methyl-5-propylbenzofuran-4-ol
InChIKey: PLRQEJPVGOQVSJ-UHFFFAOYSA-N
SMILES: ClC1=CC(CCC)=C(C2=C1OC(CC3=CC=C(C=C3)OC)=C2C)O
Biological Activity: L-656224 is an orally active, potent and selective inhibitor of leukotriene biosynthesis in intact rat and human leukocytes and CXBG mastocytoma cells (IC50 values, 18-240 nM) and of human leukocyte and porcine leukocyte 5-lipoxygenase (IC50, 4 x 10-7 M). L-656224 is promising for research of asthma and peripheral analgesic agents[1].
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L-656224 | L-656224 is an orally active, potent and selective inhibitor of leukotriene biosynthesis in intact rat and human leukocytes and CXBG mastocytoma cells (IC50 values, 18-240 nM) and of human leukocyte and porcine leukocyte 5-lipoxygenase (IC50, 4 x 10-7 M). L-656224 is promising for research of asthma and peripheral analgesic agents. | |||||||||||||||||||||
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Keywords
