104375-88-4
Chemical Structure
5’-O-DMTr-5-iodo-2’-deoxyuridine
Synonym(s): 2'-Deoxy-5'-O-DMT-5-iodouridine
- CAS No.: 104375-88-4
- Formula:C30H29IN2O7
- Molecular Weight:656.46
IUPAC Name: 1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione
InChIKey: RLDUYGSOCGOJTP-OYUWMTPXSA-N
SMILES: COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@H]4O[C@@H](N5C(NC(C(I)=C5)=O)=O)C[C@@H]4O
Biological Activity: 5’-O-DMTr-5-iodo-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5’-O-DMTr-5-iodo-2’-deoxyuridine | 5’-O-DMTr-5-iodo-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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Keywords
