1058167-74-0
![3-β-D-Ribofuranosyl-6-hydroxymethyl-furano[2,3-d]-pyrimidin-2-one Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-154029.gif "3-β-D-Ribofuranosyl-6-hydroxymethyl-furano[2,3-d]-pyrimidin-2-one Chemical Structure")
1058167-74-0
Chemical Structure
3-β-D-Ribofuranosyl-6-hydroxymethyl-furano[2,3-d]-pyrimidin-2-one
- No. CAS: 1058167-74-0
- Formula:C12H16N2O7
- Molecular Weight:300.26
IUPAC Name: 3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-(hydroxymethyl)-3,7a-dihydrofuro[2,3-d]pyrimidin-2(1H)-one
InChIKey: HYQABDKXVCTRHX-POWIHWOASA-N
SMILES: O[C@H]1[C@@H](O)[C@H](N2C(NC(OC(CO)=C3)C3=C2)=O)O[C@@H]1CO
Biological Activity: 3-β-D-Ribofuranosyl-6-hydroxymethyl-furano[2,3-d]-pyrimidin-2-one is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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3-β-D-Ribofuranosyl-6-hydroxymethyl-furano[2,3-d]-pyrimidin-2-one | 3-β-D-Ribofuranosyl-6-hydroxymethyl-furano[2,3-d]-pyrimidin-2-one is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
