108437-64-5
108437-64-5
Chemical Structure
12-OxoETE
Synonym(s): 12-KETE
- CAS No.: 108437-64-5
- Formula:C20H30O3
- Molecular Weight:318.45
IUPAC Name: (5Z,8E,10Z,14Z)-12-oxoicosa-5,8,10,14-tetraenoic acid
InChIKey: GURBRQGDZZKITB-GVIPNGEASA-N
SMILES: CCCCC/C=C\CC(/C=C\C=C\C/C=C\CCCC(O)=O)=O
Biological Activity: 12-OxoETE induces a rapid, dose dependent increase of cytoplasmic free calcium via leukotriene B4 receptor or a common activation sequence[1][2].
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12-OxoETE | 12-OxoETE induces a rapid, dose dependent increase of cytoplasmic free calcium via leukotriene B4 receptor or a common activation sequence. | |||||||||||||||||||||
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References
- [1]. Naccache PH, Leblanc Y, Rokach J, Patrignani P, Fruteau de Laclos B, Borgeat P. Calcium mobilization and right-angle light scatter responses to 12-oxo-derivatives of arachidonic acid in neutrophils: evidence for the involvement of the leukotriene B4 receptor. Biochim Biophys Acta. 1991 Dec 3;1133(1):102-6. [Content Brief]
Keywords
