1086378-73-5
Chemical Structure
CX1763
- CAS No.: 1086378-73-5
- Formula:C14H17N3O3
- Molecular Weight:275.30
InChIKey: RJSPKJWOSVQMSH-XYPYZODXSA-N
SMILES: CN([C@H]1CC[C@@H](CC1)O)C(C2=CC3=NON=C3C=C2)=O
Biological Activity: CX1763 is an AMPAR allosteric modulator. CX1763 allosterically potentiates glutamate-evoked currents, accelerates channel opening, and increases the surface levels of AMPAR containing Glur2 (R). CX1763 enhances synaptic transmission in the rat hippocampus. CX1763 improves attention in rats and attenuates amphetamine-induced hyperactivity in mice. CX1763 can be used in studies related to attention deficit hyperactivity disorder and opioid-induced respiratory depression[1].
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CX1763 | CX1763 is an AMPAR allosteric modulator. CX1763 allosterically potentiates glutamate-evoked currents, accelerates channel opening, and increases the surface levels of AMPAR containing Glur2 (R). CX1763 enhances synaptic transmission in the rat hippocampus. CX1763 improves attention in rats and attenuates amphetamine-induced hyperactivity in mice. CX1763 can be used in studies related to attention deficit hyperactivity disorder and opioid-induced respiratory depression. | |||||||||||||||||||||
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Keywords
