1086639-59-9
1086639-59-9
Chemical Structure
Y11
- CAS No.: 1086639-59-9
- Formula:C8H17BrN4O
- Molecular Weight:265.15
IUPAC Name: 2-((3r,5r,7r)-1l4,3,5,7-tetraazaadamantan-1-yl)ethan-1-ol, bromide salt
InChIKey: KRTWXNFVQFIWLI-UHFFFAOYSA-M
SMILES: OCC[N+]12C[N@](C3)C[N@](C[N@]3C2)C1.[Br-]
Biological Activity: Y11 inhibits the autophosphorylation of FAK1 by blocking the phosphorylation of Y397. Y11 increases the expression level of IL-6. Y11 is applicable for cancer research[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Y11 | 98.34% | Y11 inhibits the autophosphorylation of FAK1 by blocking the phosphorylation of Y397. Y11 increases the expression level of IL-6. Y11 is applicable for cancer research. | ||||||||||||||||||||
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References
- [1]. Golubovskaya VM, et al. A small molecule inhibitor, 1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growth. J Med Chem. 2008;51(23):7405-7416. [Content Brief]
- [2]. Keasey MP, et al. Blood vitronectin is a major activator of LIF and IL-6 in the brain through integrin-FAK and uPAR signaling. J Cell Sci. 2018;131(3):jcs202580. Published 2018 Feb 2. [Content Brief]
- [3]. Roux-Osovitz MM, et al. Trapping, tagging and tracking: Tools for the study of proteins during early development of the sea urchin. Methods Cell Biol. 2019;151:283-304. [Content Brief]
Keywords
