109304-04-3
109304-04-3
Chemical Structure
2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine
- CAS No.: 109304-04-3
- Formula:C10H12FN5O3
- Molecular Weight:269.23
IUPAC Name: (2R,3R,4S,5R)-5-(2-amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
InChIKey: REZWVJHKIBWHOX-JVZYCSMKSA-N
SMILES: O[C@H]1[C@H](F)[C@H](N(C=N2)C3=C2C=NC(N)=N3)O[C@@H]1CO
Biological Activity: 2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine | 2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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