109304-12-3
109304-12-3
Chemical Structure
2’-Deoxy-2’-fluoro-6-S-methyl-6-thio-arabino-inosine
- CAS No.: 109304-12-3
- Formula:C11H13FN4O3S
- Molecular Weight:300.31
IUPAC Name: (2R,3R,4S,5R)-4-fluoro-2-(hydroxymethyl)-5-(6-(methylthio)-9H-purin-9-yl)tetrahydrofuran-3-ol
InChIKey: LMKSOCCMDKEQQH-WCGPTHBMSA-N
SMILES: OC[C@@H]1[C@@H](O)[C@H](F)[C@H](N(C=N2)C3=C2C(SC)=NC=N3)O1
Biological Activity: 2’-Deoxy-2’-fluoro-6-S-methyl-6-thio-arabino-inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’-Deoxy-2’-fluoro-6-S-methyl-6-thio-arabino-inosine | 2’-Deoxy-2’-fluoro-6-S-methyl-6-thio-arabino-inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
