110220-55-8
110220-55-8
Chemical Structure
Methoxyamine-d3 Hydrochloride
Synonym(s): O-Methylhydroxylamine-d3 hydrochloride
- CAS No.: 110220-55-8
- Formula:CH3D3ClNO
- Molecular Weight:86.54
IUPAC Name: O-(methyl-d3)hydroxylamine hydrochloride
InChIKey: XNXVOSBNFZWHBV-NIIDSAIPSA-N
SMILES: [2H]C([2H])([2H])ON.Cl
Biological Activity: Methoxyamine-d3 (O-Methylhydroxylamine-d3) hydrochloride is the deuterium labeled Methoxyamine hydrochloride. Methoxyamine hydrochloride is an orally active and potent base excision repair (BER) inhibitor[1].
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Methoxyamine-d3 Hydrochloride | 99% | Methoxyamine-d3 (O-Methylhydroxylamine-d3) hydrochloride is the deuterium labeled Methoxyamine hydrochloride. Methoxyamine hydrochloride is an orally active and potent base excision repair (BER) inhibitor. | ||||||||||||||||||||
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Methoxyamine hydrochloride (Standard) | ≥98% | Methoxyamine hydrochloride (Standard) is the analytical standard of Methoxyamine hydrochloride. This product is intended for research and analytical applications. Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor. Methoxyamine hydrochloride binds to 3’ hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity. Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites. Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents. | ||||||||||||||||||||
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Methoxyamine hydrochloride | 98.0% | Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor. Methoxyamine hydrochloride binds to 3’ hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity. Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites. Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents. | ||||||||||||||||||||
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References
