113190-92-4
Chemical Structure
PPPA
- CAS No.: 113190-92-4
- Formula:C9H18NO5P
- Molecular Weight:251.22
IUPAC Name: (2R,4S)-4-(3-phosphonopropyl)piperidine-2-carboxylic acid
InChIKey: ABIFUJNCKIMWRZ-JGVFFNPUSA-N
SMILES: OC([C@H]1C[C@H](CCN1)CCCP(O)(O)=O)=O
Biological Activity: PPPA is a competitive NMDA receptor antagonist that displays moderate selectivity for NR2A-containing receptors[1][2].
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PPPA | PPPA is a competitive NMDA receptor antagonist that displays moderate selectivity for NR2A-containing receptors. | |||||||||||||||||||||
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- [1]. Benveniste M, Mayer ML. Effect of extracellular pH on the potency of N-methyl-D-aspartic acid receptor competitive antagonists. Mol Pharmacol. 1992 Oct;42(4):679-86. [Content Brief]
- [2]. Feng B, et al. The effect of competitive antagonist chain length on NMDA receptor subunit selectivity. Neuropharmacology. 2005 Mar;48(3):354-9. [Content Brief]
Keywords