113231-05-3
113231-05-3
Chemical Structure
Nα,Nα-Bis(carboxymethyl)-L-lysine
- CAS No.: 113231-05-3
- Formula:C10H18N2O6
- Molecular Weight:262.26
IUPAC Name: (S)-2,2'-((5-amino-1-carboxypentyl)azanediyl)diacetic acid
InChIKey: SYFQYGMJENQVQT-ZETCQYMHSA-N
SMILES: NCCCC[C@@H](C(O)=O)N(CC(O)=O)CC(O)=O
Biological Activity: Nα,Nα-Bis(carboxymethyl)-L-lysine is a competitive inhibitor of bitter taste receptor 4, with an IC50 of 59 nM. Nα,Nα-Bis(carboxymethyl)-L-lysine can be used in bitter receptors related study[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Nα,Nα-Bis(carboxymethyl)-L-lysine | 98.80% | Nα,Nα-Bis(carboxymethyl)-L-lysine is a competitive inhibitor of bitter taste receptor 4, with an IC50 of 59 nM. Nα,Nα-Bis(carboxymethyl)-L-lysine can be used in bitter receptors related study. | ||||||||||||||||||||
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Nα,Nα-Bis(carboxymethyl)-L-lysine (Standard) | ≥98% | Nα,Nα-Bis(carboxymethyl)-L-lysine (Standard) is the analytical standard of Nα,Nα-Bis(carboxymethyl)-L-lysine (HY-100047). This product is intended for research and analytical applications. Nα,Nα-Bis(carboxymethyl)-L-lysine is a competitive inhibitor of bitter taste receptor 4, with an IC50 of 59 nM. Nα,Nα-Bis(carboxymethyl)-L-lysine can be used in bitter receptors related study. | ||||||||||||||||||||
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References
- [1]. Pydi SP, et al. Amino acid derivatives as bitter taste receptor (T2R) blockers. J Biol Chem. 2014;289(36):25054-25066. [Content Brief]
- [2]. Sidhu C, et al. Regulation of Rac1 GTPase activity by quinine through G-protein and bitter taste receptor T2R4. Mol Cell Biochem. 2017;426(1-2):129-136. [Content Brief]
- [3]. Masamoto M, et al. Yoshida R. Effects of bitter receptor antagonists on behavioral lick responses of mice. Neurosci Lett. 2020;730:135041. [Content Brief]
